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Trichothiodystrophy, commonly known as TTD, is a exceptional inherited affliction that influences several elements of the human body. The hallmark of the situation is hair that's sparse and simply damaged. [from MedlinePlus Genetics]
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The signs and signs of trichothiodystrophy vary widely. Gentle circumstances may perhaps include only the hair. Much more significant scenarios also trigger delayed enhancement, sizeable intellectual incapacity, and recurrent infections; severely affected people may possibly survive only into infancy or early childhood.
People with PNH may additionally be at risk of bacterial infections due to a shortage of white blood cells (leukopenia).
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Some scientists feel that dentinogenesis imperfecta sort II and kind III, along with a affliction referred to as dentin dysplasia kind II, are actually kinds of an individual condition.
Scalp hair could also be lighter in shade than envisioned and is also fragile and easily broken. Influenced folks often simply cannot mature hair extended than a several inches. The eyebrows, eyelashes, and also other physique hair may very well be sparse too. Over time, the hair problems can continue being stable or development to accomplish scalp hair reduction (alopecia) in addition to a lower in system hair.
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Mothers of youngsters with trichothiodystrophy may possibly encounter problems all through pregnancy like pregnancy-induced high blood pressure level (preeclampsia) along with a similar issue known as HELLP syndrome which will injury the liver.